Disentanglement

Integrating multi-covariate disentanglement with counterfactual analysis on synthetic data enables cell type discovery and counterfactual predictions
CellDISECT models how cell states change across covariates and perturbations for counterfactual questions in single-cell biology; the manuscript is under review at Nature Methods.
Stathis Megas, Arian Amani, Antony Rose, Olli Dufva, Kian Shamsaie, Hesam Asadollahzadeh, Krzysztof Polanski, Muzlifah Haniffa, Sarah Amalia Teichmann, Mohammad Lotfollahi
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Integrating multi-covariate disentanglement with counterfactual analysis on synthetic data enables cell type discovery and counterfactual predictions