CellDISECT

Jun 3, 2025
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Deep Learning Single-Cell Genomics Causal Inference
Arian Amani
Arian Amani
Machine Learning Scientist

I build AI systems for drug discovery and virtual cells — bridging deep generative models, single-cell biology, and production ML to accelerate therapeutic discovery.

Publications

Integrating multi-covariate disentanglement with counterfactual analysis on synthetic data enables cell type discovery and counterfactual predictions
CellDISECT models how cell states change across covariates and perturbations, making it easier to ask counterfactual questions in single-cell biology.
Stathis Megas, Arian Amani, Antony Rose, Olli Dufva, Kian Shamsaie, Hesam Asadollahzadeh, Krzysztof Polanski, Muzlifah Haniffa, Sarah Amalia Teichmann, Mohammad Lotfollahi
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Integrating multi-covariate disentanglement with counterfactual analysis on synthetic data enables cell type discovery and counterfactual predictions